BDBM272459 US10065950, Example 303

SMILES: CC[C@@H]1Cn2cc(-c3nnc(Cc4ccc(F)cc4)s3)c(=O)c(O)c2C(=O)N1CC1CC1

InChI Key: InChIKey=ZJGPTHIOHXZVGF-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
inhibitory activity (Human immunodeficiency virus type 1 group M subtyp...)	BDBM272459 (US10065950, Example 303) Show SMILES CC[C@@H]1Cn2cc(-c3nnc(Cc4ccc(F)cc4)s3)c(=O)c(O)c2C(=O)N1CC1CC1 |r| Show InChI InChI=1S/C23H23FN4O3S/c1-2-16-11-27-12-17(20(29)21(30)19(27)23(31)28(16)10-14-3-4-14)22-26-25-18(32-22)9-13-5-7-15(24)8-6-13/h5-8,12,14,16,30H,2-4,9-11H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	25
Japan Tobacco Inc. US Patent					Assay Description The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...				US Patent US10065950 (2018) BindingDB Entry DOI: 10.7270/Q2RN39V2
					More data for this Ligand-Target Pair