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BDBM272521 US10065953, Example 3

SMILES: Cc1cc2nc(cn2c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O)-c1cccc(c1)-c1ccc(F)cc1

InChI Key: InChIKey=RKOHUDBVANMERR-LJAQVGFWSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272521   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)		BDBM272521
PNG
(US10065953, Example 3)
Show SMILES Cc1cc2nc(cn2c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O)-c1cccc(c1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C33H38FN3O3/c1-21-18-27-35-26(24-9-7-8-23(19-24)22-10-12-25(34)13-11-22)20-37(27)30(36-16-14-33(5,6)15-17-36)28(21)29(31(38)39)40-32(2,3)4/h7-13,18-20,29H,14-17H2,1-6H3,(H,38,39)/t29-/m0/s1
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US Patent
n/an/an/an/a 26n/an/an/an/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-Rluc virus was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. The NL-RLuc ...

US Patent US10065953 (2018)


BindingDB Entry DOI: 10.7270/Q2WD42KS
More data for this
Ligand-Target Pair