BDBM27288 indole derivative, 1n (S)::tert-butyl 2-[(2S)-2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl]-1H-indole-1-carboxylate

SMILES: CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@@H](Cc2c1)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=ODJWHQQYADUVIQ-QHCPKHFHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27288 (indole derivative, 1n (S) | tert-butyl 2-[(2S)-2-b...) Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@@H](Cc2c1)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	7.5	22
Tanabe Research Laboratories USA					Assay Description Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...				Bioorg Med Chem Lett 17: 3473-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.076 BindingDB Entry DOI: 10.7270/Q2HD7T00
					More data for this Ligand-Target Pair