BDBM27289 N-[5-(1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 6

SMILES: O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2[nH]1)c1ccccc1

InChI Key: InChIKey=JGPPKFSZHLHEKV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27289 (N-[5-(1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]ben...) Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2[nH]1)c1ccccc1 Show InChI InChI=1S/C23H20N2O2S/c26-28(27,21-7-2-1-3-8-21)25-20-13-16-10-11-18(12-19(16)14-20)23-15-17-6-4-5-9-22(17)24-23/h1-12,15,20,24-25H,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	7.5	22
Tanabe Research Laboratories USA					Assay Description Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...				Bioorg Med Chem Lett 17: 3473-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.076 BindingDB Entry DOI: 10.7270/Q2HD7T00
					More data for this Ligand-Target Pair