BDBM27313 indole derivative, 5h::tert-butyl 2-{2-[(3-methoxybenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate

SMILES: COc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C

InChI Key: InChIKey=CDXKPTNMOFCZKM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27313 (indole derivative, 5h | tert-butyl 2-{2-[(3-methox...) Show SMILES COc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C Show InChI InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26-11-6-5-8-20(26)17-27(31)21-13-12-19-15-23(16-22(19)14-21)30-37(33,34)25-10-7-9-24(18-25)35-4/h5-14,17-18,23,30H,15-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	960	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...				Bioorg Med Chem Lett 17: 3473-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.076 BindingDB Entry DOI: 10.7270/Q2HD7T00
					More data for this Ligand-Target Pair