BDBM27320 indole derivative, 5o::tert-butyl 2-{2-[(2-cyanobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate

SMILES: CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C#N

InChI Key: InChIKey=GWRYATMHUPAHEK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27320 (indole derivative, 5o | tert-butyl 2-{2-[(2-cyanob...) Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C#N Show InChI InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-25-10-6-4-8-20(25)17-26(32)21-13-12-19-15-24(16-23(19)14-21)31-37(34,35)27-11-7-5-9-22(27)18-30/h4-14,17,24,31H,15-16H2,1-3H3	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...				Bioorg Med Chem Lett 17: 3473-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.076 BindingDB Entry DOI: 10.7270/Q2HD7T00
					More data for this Ligand-Target Pair