BDBM27410 2-(2-aminopyrimidin-4-yl)-1-butyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 32

SMILES: CCCCn1c2CCNC(=O)c2cc1-c1ccnc(N)n1

InChI Key: InChIKey=WVSCBSTWYVXQCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27410 (2-(2-aminopyrimidin-4-yl)-1-butyl-1H,4H,5H,6H,7H-p...) Show SMILES CCCCn1c2CCNC(=O)c2cc1-c1ccnc(N)n1 Show InChI InChI=1S/C15H19N5O/c1-2-3-8-20-12-5-7-17-14(21)10(12)9-13(20)11-4-6-18-15(16)19-11/h4,6,9H,2-3,5,7-8H2,1H3,(H,17,21)(H2,16,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair