BDBM27420 2-{2-[(2-methylpropyl)amino]pyrimidin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 42

SMILES: CC(C)CNc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1

InChI Key: InChIKey=CZHPLAXUABYICD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27420 (2-{2-[(2-methylpropyl)amino]pyrimidin-4-yl}-1H,4H,...) Show SMILES CC(C)CNc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1 Show InChI InChI=1S/C15H19N5O/c1-9(2)8-18-15-17-6-4-12(20-15)13-7-10-11(19-13)3-5-16-14(10)21/h4,6-7,9,19H,3,5,8H2,1-2H3,(H,16,21)(H,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	636	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair