null

SMILES: CN1CC(C1)n1cc(C)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1

InChI Key: InChIKey=DVICYEUYFBDIJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 274211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-477] (Homo sapiens (Human))	BDBM274211 (6-(4-chlorophenyl)-5-(3,8-di methyl-[1,2,4]triazol...) Show SMILES CN1CC(C1)n1cc(C)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O/c1-14-9-19(13-30-16(3)27-28-24(14)30)32-22(17-5-7-18(26)8-6-17)23-21(25(32)33)15(2)10-31(23)20-11-29(4)12-20/h5-10,13,20,22H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9550796 (2017) BindingDB Entry DOI: 10.7270/Q2QN68SK
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM274211 (6-(4-chlorophenyl)-5-(3,8-di methyl-[1,2,4]triazol...) Show SMILES CN1CC(C1)n1cc(C)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O/c1-14-9-19(13-30-16(3)27-28-24(14)30)32-22(17-5-7-18(26)8-6-17)23-21(25(32)33)15(2)10-31(23)20-11-29(4)12-20/h5-10,13,20,22H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	7.5	30
NOVARTIS AG US Patent					Assay Description All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9550796 (2017) BindingDB Entry DOI: 10.7270/Q2QN68SK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM274211 (6-(4-chlorophenyl)-5-(3,8-di methyl-[1,2,4]triazol...) Show SMILES CN1CC(C1)n1cc(C)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O/c1-14-9-19(13-30-16(3)27-28-24(14)30)32-22(17-5-7-18(26)8-6-17)23-21(25(32)33)15(2)10-31(23)20-11-29(4)12-20/h5-10,13,20,22H,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9550796 (2017) BindingDB Entry DOI: 10.7270/Q2QN68SK
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 [60-463] (Homo sapiens (Human))	BDBM274211 (6-(4-chlorophenyl)-5-(3,8-di methyl-[1,2,4]triazol...) Show SMILES CN1CC(C1)n1cc(C)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O/c1-14-9-19(13-30-16(3)27-28-24(14)30)32-22(17-5-7-18(26)8-6-17)23-21(25(32)33)15(2)10-31(23)20-11-29(4)12-20/h5-10,13,20,22H,11-12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9550796 (2017) BindingDB Entry DOI: 10.7270/Q2QN68SK
					More data for this Ligand-Target Pair