BDBM27433 16-methyl-8-thia-3,5,10-triazatetracyclo[7.7.0.0^{2,7}.0^{11,15}]hexadeca-1(16),2(7),3,5,9,11(15)-hexaen-6-amine::pyrido-thieno-pyrimidine, 6g

SMILES: Cc1c2CCCc2nc2sc3c(N)ncnc3c12

InChI Key: InChIKey=KDVNYSFYFJOXEX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27433 (16-methyl-8-thia-3,5,10-triazatetracyclo[7.7.0.0^{...) Show SMILES Cc1c2CCCc2nc2sc3c(N)ncnc3c12 Show InChI InChI=1S/C13H12N4S/c1-6-7-3-2-4-8(7)17-13-9(6)10-11(18-13)12(14)16-5-15-10/h5H,2-4H2,1H3,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	-11.8	50	n/a	n/a	n/a	n/a	7.5	37
Roche					Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc...				Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2
					More data for this Ligand-Target Pair