BDBM27435 12-benzyl-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine::pyrido-thieno-pyrimidine, 6i

SMILES: Cc1nc2sc3c(N)ncnc3c2c(C)c1Cc1ccccc1

InChI Key: InChIKey=ARVFZPKMFCDHRI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27435 (12-benzyl-11,13-dimethyl-8-thia-3,5,10-triazatricy...) Show SMILES Cc1nc2sc3c(N)ncnc3c2c(C)c1Cc1ccccc1 Show InChI InChI=1S/C18H16N4S/c1-10-13(8-12-6-4-3-5-7-12)11(2)22-18-14(10)15-16(23-18)17(19)21-9-20-15/h3-7,9H,8H2,1-2H3,(H2,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	200	-9.50	2.00E+3	n/a	n/a	n/a	n/a	7.5	37
Roche					Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc...				Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2
					More data for this Ligand-Target Pair