BDBM27482 2-methoxy-3-phenyl-5-(pyridin-4-yl)benzamide::O-substituted diarylbenzamide, 11d

SMILES: COc1c(cc(cc1-c1ccccc1)-c1ccncc1)C(N)=O

InChI Key: InChIKey=CAVZKMMEPFAEIZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM27482 (2-methoxy-3-phenyl-5-(pyridin-4-yl)benzamide | O-s...) Show SMILES COc1c(cc(cc1-c1ccccc1)-c1ccncc1)C(N)=O Show InChI InChI=1S/C19H16N2O2/c1-23-18-16(14-5-3-2-4-6-14)11-15(12-17(18)19(20)22)13-7-9-21-10-8-13/h2-12H,1H3,(H2,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...				Bioorg Med Chem Lett 17: 3972-7 (2007) Article DOI: 10.1016/j.bmcl.2007.04.088 BindingDB Entry DOI: 10.7270/Q2QZ289W
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM27482 (2-methoxy-3-phenyl-5-(pyridin-4-yl)benzamide | O-s...) Show SMILES COc1c(cc(cc1-c1ccccc1)-c1ccncc1)C(N)=O Show InChI InChI=1S/C19H16N2O2/c1-23-18-16(14-5-3-2-4-6-14)11-15(12-17(18)19(20)22)13-7-9-21-10-8-13/h2-12H,1H3,(H2,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...				Bioorg Med Chem Lett 17: 3972-7 (2007) Article DOI: 10.1016/j.bmcl.2007.04.088 BindingDB Entry DOI: 10.7270/Q2QZ289W
					More data for this Ligand-Target Pair