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SMILES: CC(NC(=O)c1ccc(-c2cccc(c2)C(F)(F)F)c2CCN(Cc12)C(=O)NC(C)(C)C)c1nncs1

InChI Key: InChIKey=TZRBOSXUVPOENL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275034   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM275034
PNG
(N8-(1-(1,3,4-thiadiazol-2-yl)ethyl)-N2-(tert- buty...)
Show SMILES CC(NC(=O)c1ccc(-c2cccc(c2)C(F)(F)F)c2CCN(Cc12)C(=O)NC(C)(C)C)c1nncs1
Show InChI InChI=1S/C26H28F3N5O2S/c1-15(23-33-30-14-37-23)31-22(35)20-9-8-18(16-6-5-7-17(12-16)26(27,28)29)19-10-11-34(13-21(19)20)24(36)32-25(2,3)4/h5-9,12,14-15H,10-11,13H2,1-4H3,(H,31,35)(H,32,36)
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KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 659n/an/an/an/a7.025



Merck Sharp & Dohme Corp.

US Patent


Assay Description
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...

US Patent US9877957 (2018)


BindingDB Entry DOI: 10.7270/Q2Z60R2C
More data for this
Ligand-Target Pair