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SMILES: CC(C)(C)NC(=O)N1CCc2c(C1)c(ccc2-c1cccc(OC(F)(F)F)c1)C(=O)NCc1cccc2ccnn12

InChI Key: InChIKey=OAOADSKURIQZDB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275041   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM275041
PNG
(N2-(tert-butyl)-N8-(pyrazolo[1,5-a]pyridin-7- ylme...)
Show SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(ccc2-c1cccc(OC(F)(F)F)c1)C(=O)NCc1cccc2ccnn12
Show InChI InChI=1S/C30H30F3N5O3/c1-29(2,3)36-28(40)37-15-13-24-23(19-6-4-9-22(16-19)41-30(31,32)33)10-11-25(26(24)18-37)27(39)34-17-21-8-5-7-20-12-14-35-38(20)21/h4-12,14,16H,13,15,17-18H2,1-3H3,(H,34,39)(H,36,40)
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KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 149n/an/an/an/a7.025



Merck Sharp & Dohme Corp.

US Patent


Assay Description
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...

US Patent US9877957 (2018)


BindingDB Entry DOI: 10.7270/Q2Z60R2C
More data for this
Ligand-Target Pair