BDBM275084 US10221195, Example 26::US9879032, Example 26

SMILES: COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OC[C@@H](NC(=O)c2c1)C(C)C

InChI Key: InChIKey=JAZYGFKIVPSKSS-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM275084 (US10221195, Example 26 | US9879032, Example 26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OC[C@@H](NC(=O)c2c1)C(C)C |r| Show InChI InChI=1S/C18H20ClN3O5S/c1-10(2)14-9-27-18-13(17(23)21-14)7-12(8-20-18)22-28(24,25)16-6-11(19)4-5-15(16)26-3/h4-8,10,14,22H,9H2,1-3H3,(H,21,23)/t14-/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited; Sanford Burnham Prebys Medical Discovery Institute US Patent					Assay Description COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...				US Patent US10221195 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2D83
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM275084 (US10221195, Example 26 | US9879032, Example 26) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OC[C@@H](NC(=O)c2c1)C(C)C |r| Show InChI InChI=1S/C18H20ClN3O5S/c1-10(2)14-9-27-18-13(17(23)21-14)7-12(8-20-18)22-28(24,25)16-6-11(19)4-5-15(16)26-3/h4-8,10,14,22H,9H2,1-3H3,(H,21,23)/t14-/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	25
Daiichi Sankyo Company, Limited; Sandford Burnham Prebys Medical Discovery Institute US Patent					Assay Description COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In...				US Patent US9879032 (2018) BindingDB Entry DOI: 10.7270/Q2F76FKB
					More data for this Ligand-Target Pair