BDBM275463 US9879013, 8
SMILES: Nc1ncnc2n(C3CN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12
InChI Key: InChIKey=JDJIUBQAXIUQGA-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LCK/BTK (Homo sapiens (Human)) | BDBM275463 (US9879013, 8) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR... | US Patent US9879013 (2018) BindingDB Entry DOI: 10.7270/Q2X63PZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
LynA/BTK (Homo sapiens (Human)) | BDBM275463 (US9879013, 8) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.59E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR... | US Patent US9879013 (2018) BindingDB Entry DOI: 10.7270/Q2X63PZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fyn/BTK (Homo sapiens (Human)) | BDBM275463 (US9879013, 8) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.53E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR... | US Patent US9879013 (2018) BindingDB Entry DOI: 10.7270/Q2X63PZ1 | |||||||||||
More data for this Ligand-Target Pair |