BDBM275769 Hexadecyloxypropyl-cyclic cidofovir::US10071110, Compound 1-O-hexadecylpropanediol-3-cCDV::US10071110, Compound HDP-cCDV
SMILES: CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1
InChI Key: InChIKey=SLYMJSGMJWGMJB-UHFFFAOYSA-N
Data: 5 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ... | US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ... | US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human herpes virus 5 capsid protein P40 (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...) | BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L... | US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ... | US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM275769 (Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <30 | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ... | US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9 | |||||||||||
More data for this Ligand-Target Pair |