BDBM27593 2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-4-methyl-1H-pyrazol-5-yl]sulfanyl}acetamido)phenyl]phenyl}acetic acid::pyrazolyl compound, 30

SMILES: Cc1cnn(c1SCC(=O)Nc1ccc(cc1Cl)-c1ccc(CC(O)=O)cc1)-c1ccc(C)cc1Cl

InChI Key: InChIKey=JVAVCUSDGJWPTQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase Mutant (103N/181C) (Human immunodeficiency virus type 1)	BDBM27593 (2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...) Show SMILES Cc1cnn(c1SCC(=O)Nc1ccc(cc1Cl)-c1ccc(CC(O)=O)cc1)-c1ccc(C)cc1Cl Show InChI InChI=1S/C27H23Cl2N3O3S/c1-16-3-10-24(22(29)11-16)32-27(17(2)14-30-32)36-15-25(33)31-23-9-8-20(13-21(23)28)19-6-4-18(5-7-19)12-26(34)35/h3-11,13-14H,12,15H2,1-2H3,(H,31,33)(H,34,35)	PDB MMDB B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd.					Assay Description IC50 values for wild-type and mutant RTs were obtained from a scintillation prox imity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value repres...				Bioorg Med Chem Lett 19: 1199-205 (2009) Article DOI: 10.1016/j.bmcl.2008.12.074 BindingDB Entry DOI: 10.7270/Q2ZG6QKQ
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1 group M subtyp...)	BDBM27593 (2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...) Show SMILES Cc1cnn(c1SCC(=O)Nc1ccc(cc1Cl)-c1ccc(CC(O)=O)cc1)-c1ccc(C)cc1Cl Show InChI InChI=1S/C27H23Cl2N3O3S/c1-16-3-10-24(22(29)11-16)32-27(17(2)14-30-32)36-15-25(33)31-23-9-8-20(13-21(23)28)19-6-4-18(5-7-19)12-26(34)35/h3-11,13-14H,12,15H2,1-2H3,(H,31,33)(H,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	37
Boehringer Ingelheim (Canada) Ltd.					Assay Description IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...				Bioorg Med Chem Lett 19: 1199-205 (2009) Article DOI: 10.1016/j.bmcl.2008.12.074 BindingDB Entry DOI: 10.7270/Q2ZG6QKQ
					More data for this Ligand-Target Pair