BDBM278965 5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxybut-2-ynyl]-3-methyl-tetrahydrofuran-2-yl]-6H-thiazolo[4,5-d]pyrimidine-2,7-dione::US10040815, Example 29::US10618929, Example 29

SMILES: CC#C[C@H](O)[C@@H]1C[C@@H](C)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O

InChI Key:

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 278965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM278965 (5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxybut-2-ynyl]...) Show SMILES CC#C[C@H](O)[C@@H]1C[C@@H](C)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat. #: hkb-ht1r7, San Diego, Calif., USA). These cells were designed for studyin...				US Patent US10618929 (2020)
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM278965 (5-Amino-3-[(2R,3R,5S)-5-[(1S)-1-hydroxybut-2-ynyl]...) Show SMILES CC#C[C@H](O)[C@@H]1C[C@@H](C)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat.#: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying...				US Patent US10040815 (2018) BindingDB Entry DOI: 10.7270/Q21V5H13
					More data for this Ligand-Target Pair