BDBM28001 2-[benzyl(ethyl)amino]-4-cyclohexyl-N-(2-phenoxyethyl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 11b

SMILES: CCN(Cc1ccccc1)c1ncc(C(=O)NCCOc2ccccc2)c(n1)C1CCCCC1

InChI Key: InChIKey=PBTICVOUOMVVLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM28001 (2-[benzyl(ethyl)amino]-4-cyclohexyl-N-(2-phenoxyet...) Show SMILES CCN(Cc1ccccc1)c1ncc(C(=O)NCCOc2ccccc2)c(n1)C1CCCCC1 Show InChI InChI=1S/C28H34N4O2/c1-2-32(21-22-12-6-3-7-13-22)28-30-20-25(26(31-28)23-14-8-4-9-15-23)27(33)29-18-19-34-24-16-10-5-11-17-24/h3,5-7,10-13,16-17,20,23H,2,4,8-9,14-15,18-19,21H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.5	37
Bristol-Myers Squibb Company					Assay Description Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...				J Med Chem 52: 1204-8 (2009) Article DOI: 10.1021/jm801178c BindingDB Entry DOI: 10.7270/Q2416VCR
					More data for this Ligand-Target Pair