BDBM280616 US10030020, Example 161::US10781211, Example 161

SMILES: CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1

InChI Key: InChIKey=YQVIQDIVZOZKRT-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 280616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair