null

SMILES: FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F

InChI Key: InChIKey=XBZRKORYNMCHJK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 280631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Mus musculus (mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280631 (US10030020, Example 176 | US10781211, Example 176) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc(OC3CCS(=O)(=O)CC3)cc(c2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C25H29F9N2O5S/c26-23(27,28)17-12-16(13-19(14-17)40-18-2-10-42(38,39)11-3-18)15-36-7-1-4-22(36)5-8-35(9-6-22)21(37)41-20(24(29,30)31)25(32,33)34/h12-14,18,20H,1-11,15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair