BDBM280644 US10030020, Example 189::US10781211, Example 189

SMILES: CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=HXHYUYZTCNPDSJ-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 280644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280644 (US10030020, Example 189 | US10781211, Example 189) Show SMILES CN1CCN(CC1)c1c(Cl)cccc1CN1CC2(CC1(C)C)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H35ClF6N4O2/c1-23(2)16-24(7-9-36(10-8-24)22(38)39-21(25(28,29)30)26(31,32)33)17-37(23)15-18-5-4-6-19(27)20(18)35-13-11-34(3)12-14-35/h4-6,21H,7-17H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair