BDBM280650 US10030020, Example 195

SMILES: CC1(CN(CCO1)c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F)C(O)=O

InChI Key: InChIKey=BQHWYVYOCHFRCA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 280650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280650 (US10030020, Example 195) Show SMILES CC1(CN(CCO1)c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C26H30F9N3O5/c1-22(20(39)40)15-37(9-10-42-22)18-12-16(11-17(13-18)24(27,28)29)14-38-6-2-3-23(38)4-7-36(8-5-23)21(41)43-19(25(30,31)32)26(33,34)35/h11-13,19H,2-10,14-15H2,1H3,(H,39,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280650 (US10030020, Example 195) Show SMILES CC1(CN(CCO1)c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C26H30F9N3O5/c1-22(20(39)40)15-37(9-10-42-22)18-12-16(11-17(13-18)24(27,28)29)14-38-6-2-3-23(38)4-7-36(8-5-23)21(41)43-19(25(30,31)32)26(33,34)35/h11-13,19H,2-10,14-15H2,1H3,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD2 (Mus musculus (Mouse))	BDBM280650 (US10030020, Example 195) Show SMILES CC1(CN(CCO1)c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C26H30F9N3O5/c1-22(20(39)40)15-37(9-10-42-22)18-12-16(11-17(13-18)24(27,28)29)14-38-6-2-3-23(38)4-7-36(8-5-23)21(41)43-19(25(30,31)32)26(33,34)35/h11-13,19H,2-10,14-15H2,1H3,(H,39,40)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM280650 (US10030020, Example 195) Show SMILES CC1(CN(CCO1)c1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C26H30F9N3O5/c1-22(20(39)40)15-37(9-10-42-22)18-12-16(11-17(13-18)24(27,28)29)14-38-6-2-3-23(38)4-7-36(8-5-23)21(41)43-19(25(30,31)32)26(33,34)35/h11-13,19H,2-10,14-15H2,1H3,(H,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair