BDBM280653 US10030020, Example 198::US10781211, Example 198

SMILES: OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCCC11CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C#C

InChI Key: InChIKey=FOKOSNLZNLWGTQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM280653 (US10030020, Example 198 | US10781211, Example 198) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCCC11CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C#C Show InChI InChI=1S/C27H31F6N3O4/c1-2-18-4-5-20(21(16-18)34-12-6-19(7-13-34)22(37)38)17-36-11-3-8-25(36)9-14-35(15-10-25)24(39)40-23(26(28,29)30)27(31,32)33/h1,4-5,16,19,23H,3,6-15,17H2,(H,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description Human: Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with ...				US Patent US10781211 (2020)
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280653 (US10030020, Example 198 | US10781211, Example 198) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCCC11CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C#C Show InChI InChI=1S/C27H31F6N3O4/c1-2-18-4-5-20(21(16-18)34-12-6-19(7-13-34)22(37)38)17-36-11-3-8-25(36)9-14-35(15-10-25)24(39)40-23(26(28,29)30)27(31,32)33/h1,4-5,16,19,23H,3,6-15,17H2,(H,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair