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SMILES: CCn1c(C)c(C)nc1Sc1ccc(Nc2c(cnc3cc(NCCCN(CCO)CCO)c(OC)cc23)C#N)cc1Cl

InChI Key: InChIKey=RJPABBGSGKDJIV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28096   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM28096
PNG
(3-cyanoquinoline, 21 | 7-({3-[bis(2-hydroxyethyl)a...)
Show SMILES CCn1c(C)c(C)nc1Sc1ccc(Nc2c(cnc3cc(NCCCN(CCO)CCO)c(OC)cc23)C#N)cc1Cl
Show InChI InChI=1S/C31H38ClN7O3S/c1-5-39-21(3)20(2)36-31(39)43-29-8-7-23(15-25(29)32)37-30-22(18-33)19-35-26-17-27(28(42-4)16-24(26)30)34-9-6-10-38(11-13-40)12-14-41/h7-8,15-17,19,34,40-41H,5-6,9-14H2,1-4H3,(H,35,37)
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Similars
Article
PubMed
n/an/a 26n/an/an/an/a7.522



Wyeth Research



Assay Description
Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...

Bioorg Med Chem Lett 19: 62-6 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.037
BindingDB Entry DOI: 10.7270/Q2M32T38
More data for this
Ligand-Target Pair