BDBM281045 (7S,10S,13S)-13-((1H-Indol-3-yl)methyl)-10-(4-aminobutyl)-7-(3-aminopropyl)-3-fluoro-12-methyl-6,7,9,10,12,13,15,16-octahydrobenzo[b]pyrido[3,2-p][1,5,8,11,14]thiatetraazacycloheptadecine-8,11,14(5H)-trione::US10030047, Example 226
SMILES: CN1[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCc2ccccc2Sc2ncc(F)cc2CN[C@@H](CCCN)C(=O)N[C@@H](CCCCN)C1=O
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adhesin Ata autotransporter (Acinetobacter baumannii (strain ATCC 17978 / CIP 5...) | BDBM281045 ((7S,10S,13S)-13-((1H-Indol-3-yl)methyl)-10-(4-amin...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The in vitro antimicrobial activity of the compounds was alternatively determined according to the following procedure:The assay used a 10-points Iso... | US Patent US10030047 (2018) BindingDB Entry DOI: 10.7270/Q2XW4MTP | |||||||||||
More data for this Ligand-Target Pair |