BDBM28136 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(2-methoxybenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)16

SMILES: [H][C@]1(CCc2c(C1)[nH]c1ccc(Cl)cc21)[C@@](C)(C(=O)OC)S(=O)(=O)c1ccccc1OC

InChI Key: InChIKey=GYQVWNOSYMGCOY-FATZIPQQSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM28136 (methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...) Show SMILES [H][C@]1(CCc2c(C1)[nH]c1ccc(Cl)cc21)[C@@](C)(C(=O)OC)S(=O)(=O)c1ccccc1OC |r| Show InChI InChI=1S/C23H24ClNO5S/c1-23(22(26)30-3,31(27,28)21-7-5-4-6-20(21)29-2)14-8-10-16-17-13-15(24)9-11-18(17)25-19(16)12-14/h4-7,9,11,13-14,25H,8,10,12H2,1-3H3/t14-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	3.16E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd					Assay Description LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...				Bioorg Med Chem Lett 19: 1654-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.109 BindingDB Entry DOI: 10.7270/Q2BK19PN
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM28136 (methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...) Show SMILES [H][C@]1(CCc2c(C1)[nH]c1ccc(Cl)cc21)[C@@](C)(C(=O)OC)S(=O)(=O)c1ccccc1OC |r| Show InChI InChI=1S/C23H24ClNO5S/c1-23(22(26)30-3,31(27,28)21-7-5-4-6-20(21)29-2)14-8-10-16-17-13-15(24)9-11-18(17)25-19(16)12-14/h4-7,9,11,13-14,25H,8,10,12H2,1-3H3/t14-,23+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+3	n/a	2.30E+3	n/a	n/a	7.4	22
F. Hoffmann-La Roche Ltd					Assay Description LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...				Bioorg Med Chem Lett 19: 1654-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.109 BindingDB Entry DOI: 10.7270/Q2BK19PN
					More data for this Ligand-Target Pair