BDBM281632 US10022461, Compound 101

SMILES: c1cc2ccncc2n1-c1ccc(cn1)-c1ccccn1

InChI Key: InChIKey=OKOKVTYZKINBHL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM281632 (US10022461, Compound 101) Show SMILES c1cc2ccncc2n1-c1ccc(cn1)-c1ccccn1 Show InChI InChI=1S/C17H12N4/c1-2-8-19-15(3-1)14-4-5-17(20-11-14)21-10-7-13-6-9-18-12-16(13)21/h1-12H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.14	-12.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...				US Patent US10022461 (2018) BindingDB Entry DOI: 10.7270/Q2959KK6
					More data for this Ligand-Target Pair