BDBM282610 US9884828, 2-105
SMILES: C[C@@H](Nc1c(nnc2cc(ccc12)-c1cncc2ccccc12)C(N)=O)C1CC1
InChI Key: InChIKey=DSCYWJSAEGYSEI-CYBMUJFWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM282610 (US9884828, 2-105) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 380 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Imago Pharmaceuticals, Inc. US Patent | Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v... | US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW | |||||||||||
More data for this Ligand-Target Pair |