BDBM282658 US9884828, 4-190

SMILES: COc1ncccc1Nc1ccc2c(NC(C)C)c(nnc2c1)C(N)=O

InChI Key: InChIKey=NMOLGFQOIIFLCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282658   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM282658 (US9884828, 4-190) Show SMILES COc1ncccc1Nc1ccc2c(NC(C)C)c(nnc2c1)C(N)=O Show InChI InChI=1S/C18H20N6O2/c1-10(2)21-15-12-7-6-11(9-14(12)23-24-16(15)17(19)25)22-13-5-4-8-20-18(13)26-3/h4-10,22H,1-3H3,(H2,19,25)(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.5	25
Imago Pharmaceuticals, Inc. US Patent					Assay Description Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...				US Patent US9884828 (2018) BindingDB Entry DOI: 10.7270/Q2NG4SNW
					More data for this Ligand-Target Pair