BDBM285 Coumarin-Based, DNA Gyrase Inhibitor::RU 64136::{[7-({3-hydroxy-5-methoxy-6-methyl-4-[(5-methyl-1H-pyrrol-2-yl)carbonyloxy]oxan-2-yl}oxy)-8-methyl-2-oxo-2H-chromen-4-yl]methyl}phosphonate
SMILES: COC1C(C)OC(Oc2ccc3c(CP([O-])([O-])=O)cc(=O)oc3c2C)C(O)C1OC(=O)c1ccc(C)[nH]1
InChI Key: InChIKey=XHIGNZUIQBYTLT-UHFFFAOYSA-L
Data: 1 ITC
Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
DNA Gyrase (Escherichia coli) | BDBM285 (Coumarin-Based, DNA Gyrase Inhibitor | RU 64136 | ...) | GoogleScholar PDB | PC cid PC sid | -8.38 | -4.09 | -4.30 | 6.15 | 7.5 | 25 | |
UMR CNRS 6032 | Biochemistry 41: 7217-23 (2002) |