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SMILES: Cc1c(OCc2cccc(c2)C#N)cccc1N1CCNCC1

InChI Key: InChIKey=LVESXSHMCQYEOI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28587   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM28587
PNG
(3-[2-methyl-3-(piperazin-1-yl)phenoxymethyl]benzon...)
Show SMILES Cc1c(OCc2cccc(c2)C#N)cccc1N1CCNCC1
Show InChI InChI=1S/C19H21N3O/c1-15-18(22-10-8-21-9-11-22)6-3-7-19(15)23-14-17-5-2-4-16(12-17)13-20/h2-7,12,21H,8-11,14H2,1H3
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Similars
Article
PubMed
 15.3 -10.5n/an/an/an/an/a7.522



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...

Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair