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SMILES: O=C(Nc1ccc2occ(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1

InChI Key: InChIKey=FCEFQRNGVCNQCP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM286081 (1-benzyl-N-(3-(morpholinomethyl)benzofuran-5-yl)-1...) Show SMILES O=C(Nc1ccc2occ(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O3/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-23-22(12-21)20(17-31-23)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...				US Patent US10081632 (2018) BindingDB Entry DOI: 10.7270/Q2VT1V45
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286081 (1-benzyl-N-(3-(morpholinomethyl)benzofuran-5-yl)-1...) Show SMILES O=C(Nc1ccc2occ(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O3/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-23-22(12-21)20(17-31-23)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGNS US Patent					Assay Description Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...				US Patent US10758530 (2020) BindingDB Entry DOI: 10.7270/Q20R9SGD
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM286081 (1-benzyl-N-(3-(morpholinomethyl)benzofuran-5-yl)-1...) Show SMILES O=C(Nc1ccc2occ(CN3CCOCC3)c2c1)c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N4O3/c29-24(19-13-25-28(16-19)14-18-4-2-1-3-5-18)26-21-6-7-23-22(12-21)20(17-31-23)15-27-8-10-30-11-9-27/h1-7,12-13,16-17H,8-11,14-15H2,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PHOENIX MOLECULAR DESIGN US Patent					Assay Description Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...				US Patent US9771366 (2017) BindingDB Entry DOI: 10.7270/Q2862JK5
					More data for this Ligand-Target Pair