null
SMILES: C[C@@H](Oc1nccc(C2CCNCC2)c1C)c1cccc(Cl)c1
InChI Key: InChIKey=NZCHNSFMTNOSTL-CQSZACIVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28618 (2-[(1R)-1-(3-chlorophenyl)ethoxy]-3-methyl-4-(pipe...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 208 | -9.11 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair |