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BDBM28633 2-methyl-3-(piperidin-4-yl)phenyl 4-methylbenzene-1-sulfonate::tolylpiperidine, 18j

SMILES: Cc1ccc(cc1)S(=O)(=O)Oc1cccc(C2CCNCC2)c1C

InChI Key: InChIKey=NYGLNRNYYSXQTL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28633   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM28633
PNG
(2-methyl-3-(piperidin-4-yl)phenyl 4-methylbenzene-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1cccc(C2CCNCC2)c1C
Show InChI InChI=1S/C19H23NO3S/c1-14-6-8-17(9-7-14)24(21,22)23-19-5-3-4-18(15(19)2)16-10-12-20-13-11-16/h3-9,16,20H,10-13H2,1-2H3
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PC cid
PC sid
UniChem
Article
PubMed
28.9 -10.3n/an/an/an/an/an/a25



Pfizer



Assay Description
Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...


Bioorg Med Chem Lett 19: 2409-12 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q24T6GP5
More data for this
Ligand-Target Pair