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SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3cc(F)cc(c3)-c3cnc(OC)nc3)cc(OC)cc2o1

InChI Key: InChIKey=IBYQHLQGHGOYAX-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286464   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proteinase-activated receptor 4


(Homo sapiens (Human))		BDBM286464
PNG
(6-(4-((3-Fluoro-5-(2-methoxypyrimidin-5-yl)benzyl)...)
Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cc(F)cc(c3)-c3cnc(OC)nc3)cc(OC)cc2o1
Show InChI InChI=1S/C26H20FN5O5S/c1-33-18-7-21(36-13-14-4-15(6-17(27)5-14)16-10-28-24(34-2)29-11-16)19-9-23(37-22(19)8-18)20-12-32-25(30-20)38-26(31-32)35-3/h4-12H,13H2,1-3H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.390n/an/an/an/an/a25



Bristol-Myers Squibb Company; Universite De Montreal

US Patent


Assay Description
The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...

US Patent US9518064 (2016)


BindingDB Entry DOI: 10.7270/Q2TT4SZX
More data for this
Ligand-Target Pair