null

SMILES: CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(COC)COC)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C

InChI Key: InChIKey=GAYHXURSEKSYLW-ILPBLYQGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human))	BDBM286575 (US9566312, Compound 2.11) Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(COC)COC)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C64H115N11O14/c1-26-28-29-40(13)53(76)52-57(80)67-45(27-2)60(83)69(17)43(16)59(82)74(22)51(44(33-88-24)34-89-25)56(79)68-49(38(9)10)63(86)70(18)46(30-35(3)4)55(78)65-41(14)54(77)66-42(15)58(81)71(19)47(31-36(5)6)61(84)72(20)48(32-37(7)8)62(85)73(21)50(39(11)12)64(87)75(52)23/h26,28,35-53,76H,27,29-34H2,1-25H3,(H,65,78)(H,66,77)(H,67,80)(H,68,79)/b28-26+/t40-,41+,42-,43-,45+,46+,47+,48+,49+,50+,51+,52+,53-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.90	n/a	n/a	n/a	7.4	n/a
Novartis AG US Patent					Assay Description Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...				US Patent US9566312 (2017) BindingDB Entry DOI: 10.7270/Q2K939J1
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Homo sapiens (Human))	BDBM286575 (US9566312, Compound 2.11) Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(COC)COC)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C64H115N11O14/c1-26-28-29-40(13)53(76)52-57(80)67-45(27-2)60(83)69(17)43(16)59(82)74(22)51(44(33-88-24)34-89-25)56(79)68-49(38(9)10)63(86)70(18)46(30-35(3)4)55(78)65-41(14)54(77)66-42(15)58(81)71(19)47(31-36(5)6)61(84)72(20)48(32-37(7)8)62(85)73(21)50(39(11)12)64(87)75(52)23/h26,28,35-53,76H,27,29-34H2,1-25H3,(H,65,78)(H,66,77)(H,67,80)(H,68,79)/b28-26+/t40-,41+,42-,43-,45+,46+,47+,48+,49+,50+,51+,52+,53-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.20	n/a	n/a	n/a	7.4	n/a
Novartis AG US Patent					Assay Description Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...				US Patent US9566312 (2017) BindingDB Entry DOI: 10.7270/Q2K939J1
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase B (Homo sapiens (Human))	BDBM286575 (US9566312, Compound 2.11) Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(COC)COC)N(C)C(=O)[C@@H](C)N(C)C1=O)C(C)C |r| Show InChI InChI=1S/C64H115N11O14/c1-26-28-29-40(13)53(76)52-57(80)67-45(27-2)60(83)69(17)43(16)59(82)74(22)51(44(33-88-24)34-89-25)56(79)68-49(38(9)10)63(86)70(18)46(30-35(3)4)55(78)65-41(14)54(77)66-42(15)58(81)71(19)47(31-36(5)6)61(84)72(20)48(32-37(7)8)62(85)73(21)50(39(11)12)64(87)75(52)23/h26,28,35-53,76H,27,29-34H2,1-25H3,(H,65,78)(H,66,77)(H,67,80)(H,68,79)/b28-26+/t40-,41+,42-,43-,45+,46+,47+,48+,49+,50+,51+,52+,53-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.30	n/a	n/a	n/a	7.4	n/a
Novartis AG US Patent					Assay Description Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...				US Patent US9566312 (2017) BindingDB Entry DOI: 10.7270/Q2K939J1
					More data for this Ligand-Target Pair