BDBM28678 5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoquinoline-2-)sulfonyl]benzene}amido)benzoic acid::Anthranilic acid deriv., 17

SMILES: OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1

InChI Key: InChIKey=OIBRXGCFFJNTAB-UHFFFAOYSA-N

Data: 6 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	794	n/a	n/a	7.0	22
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARgamma				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARalpha				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARdelta				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28678 (5-chloro-2-({3-[(7-chloro-1,2,3,4-tetrahydroisoqui...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccc(Cl)cc2C1 Show InChI InChI=1S/C23H18Cl2N2O5S/c24-17-5-4-14-8-9-27(13-16(14)10-17)33(31,32)19-3-1-2-15(11-19)22(28)26-21-7-6-18(25)12-20(21)23(29)30/h1-7,10-12H,8-9,13H2,(H,26,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair