BDBM28693 2-({3-[(7-methoxy-1H-indole-1-)sulfonyl]benzene}amido)-5-methylbenzoic acid::Anthranilic acid deriv., 31

SMILES: COc1cccc2ccn(c12)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(C)cc1C(O)=O

InChI Key: InChIKey=DHVJWXQNKUKRQP-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28693 (2-({3-[(7-methoxy-1H-indole-1-)sulfonyl]benzene}am...) Show SMILES COc1cccc2ccn(c12)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(C)cc1C(O)=O Show InChI InChI=1S/C24H20N2O6S/c1-15-9-10-20(19(13-15)24(28)29)25-23(27)17-6-3-7-18(14-17)33(30,31)26-12-11-16-5-4-8-21(32-2)22(16)26/h3-14H,1-2H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	631	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28693 (2-({3-[(7-methoxy-1H-indole-1-)sulfonyl]benzene}am...) Show SMILES COc1cccc2ccn(c12)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(C)cc1C(O)=O Show InChI InChI=1S/C24H20N2O6S/c1-15-9-10-20(19(13-15)24(28)29)25-23(27)17-6-3-7-18(14-17)33(30,31)26-12-11-16-5-4-8-21(32-2)22(16)26/h3-14H,1-2H3,(H,25,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28693 (2-({3-[(7-methoxy-1H-indole-1-)sulfonyl]benzene}am...) Show SMILES COc1cccc2ccn(c12)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(C)cc1C(O)=O Show InChI InChI=1S/C24H20N2O6S/c1-15-9-10-20(19(13-15)24(28)29)25-23(27)17-6-3-7-18(14-17)33(30,31)26-12-11-16-5-4-8-21(32-2)22(16)26/h3-14H,1-2H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair