BDBM28765 2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-phenyl-1,2-oxazol-3-yl)methoxy]phenyl}acetic acid::trisubstituted isoxazole, 11a

SMILES: OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1

InChI Key: InChIKey=JHDUFKJHBFYHOS-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28765 (2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...) Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28765 (2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...) Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28765 (2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...) Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair