BDBM28774 2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-(2-methylphenyl)-1,2-oxazol-3-yl)phenyl]acetic acid::trisubstituted isoxazole, 17i

SMILES: Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1

InChI Key: InChIKey=MAJGTGCBCFNXIJ-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28774 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28774 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28774 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair