BDBM287918 US10087144, Compound 118

SMILES: OC(=O)CNC(=O)c1cn(Cc2ccccc2)c2ccc(Br)cc2c1=O

InChI Key: InChIKey=DCGZTYHEPAHZED-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor 3 (Mus musculus)	BDBM287918 (US10087144, Compound 118) Show SMILES OC(=O)CNC(=O)c1cn(Cc2ccccc2)c2ccc(Br)cc2c1=O Show InChI InChI=1S/C19H15BrN2O4/c20-13-6-7-16-14(8-13)18(25)15(19(26)21-9-17(23)24)11-22(16)10-12-4-2-1-3-5-12/h1-8,11H,9-10H2,(H,21,26)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
UCL Business PLC US Patent					Assay Description Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...				US Patent US10087144 (2018) BindingDB Entry DOI: 10.7270/Q2CN75XD
					More data for this Ligand-Target Pair