BDBM287928 US10087144, Compound 187

SMILES: OC(=O)C(Cc1ccccc1)NC(=O)c1cn(Cc2ccccc2)c2ccc(Br)cc2c1=O

InChI Key: InChIKey=BVEGDDFOKVIMTP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor 3 (Mus musculus)	BDBM287928 (US10087144, Compound 187) Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)c1cn(Cc2ccccc2)c2ccc(Br)cc2c1=O Show InChI InChI=1S/C26H21BrN2O4/c27-19-11-12-23-20(14-19)24(30)21(16-29(23)15-18-9-5-2-6-10-18)25(31)28-22(26(32)33)13-17-7-3-1-4-8-17/h1-12,14,16,22H,13,15H2,(H,28,31)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
UCL Business PLC US Patent					Assay Description Male rats (Sprague-Dawley; 200-250 g) were stunned and killed by cervical dislocation. The mesentery was removed and third-order arteries mounted in ...				US Patent US10087144 (2018) BindingDB Entry DOI: 10.7270/Q2CN75XD
					More data for this Ligand-Target Pair