null

SMILES: CCN1C[C@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O

InChI Key: InChIKey=YOJVOPADDVTIJH-IPVJXJPOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Nef (Human immunodeficiency virus type 1 (isolate BRU/L...)	BDBM288058 (N-(2,4-difluorobenzyl)-2'- ethyl-cis-3,9'-dihydrox...) Show SMILES CCN1C[C@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O |r,wU:4.8,wD:6.6,(8.67,1.86,;7.34,2.63,;6,1.86,;6,.32,;4.67,-.45,;5.76,-1.54,;4.67,-2.63,;4.67,-4.17,;3.58,-1.54,;3.33,.32,;2,-.45,;.67,.32,;-.67,-.45,;-.67,-1.99,;-2,.32,;-3.33,-.45,;-4.67,.32,;-4.67,1.86,;-6,2.63,;-7.34,1.86,;-8.67,2.63,;-7.34,.32,;-6,-.45,;-6,-1.99,;.67,1.86,;-.67,2.63,;2,2.63,;2,4.17,;3.33,1.86,;4.67,2.63,;4.67,4.17,)| Show InChI InChI=1S/C21H21F2N3O5/c1-2-25-10-21(6-13(27)7-21)26-9-14(17(28)18(29)16(26)20(25)31)19(30)24-8-11-3-4-12(22)5-15(11)23/h3-5,9,13,27,29H,2,6-8,10H2,1H3,(H,24,30)/t13-,21+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	25
JAPAN TOBACCO INC. US Patent					Assay Description The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...				US Patent US10087178 (2018) BindingDB Entry DOI: 10.7270/Q20C4XSD
					More data for this Ligand-Target Pair