BDBM289443 5-(2-cyclopropyl-1-(3-((2-methoxyethyl)(methyl)amino)bicyo[1.1.1]pentan-1-yl)-1H-imidazol-4-yl)-3-(trifluoromethoxy)pyridin-2-amine::US10093664, Example 24

SMILES: COCCN(C)C12CC(C1)(C2)n1cc(nc1C1CC1)-c1cnc(N)c(OC(F)(F)F)c1

InChI Key: InChIKey=COBKPMKFGKGNAK-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM289443 (5-(2-cyclopropyl-1-(3-((2-methoxyethyl)(methyl)ami...) Show SMILES COCCN(C)C12CC(C1)(C2)n1cc(nc1C1CC1)-c1cnc(N)c(OC(F)(F)F)c1 Show InChI InChI=1S/C21H26F3N5O2/c1-28(5-6-30-2)19-10-20(11-19,12-19)29-9-15(27-18(29)13-3-4-13)14-7-16(17(25)26-8-14)31-21(22,23)24/h7-9,13H,3-6,10-12H2,1-2H3,(H2,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...				US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ
					More data for this Ligand-Target Pair