BDBM28947 (2S,3S)-2-{[(4-chlorophenyl)methyl]amino}-3-methylpentan-1-ol::benzylamino methylpentanol, 3c

SMILES: CC[C@H](C)[C@@H](CO)NCc1ccc(Cl)cc1

InChI Key: InChIKey=IYTKIHLGDAXONX-GXFFZTMASA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1 (Homo sapiens (Human))	BDBM28947 ((2S,3S)-2-{[(4-chlorophenyl)methyl]amino}-3-methyl...) Show SMILES CC[C@H](C)[C@@H](CO)NCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H20ClNO/c1-3-10(2)13(9-16)15-8-11-4-6-12(14)7-5-11/h4-7,10,13,15-16H,3,8-9H2,1-2H3/t10-,13+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...				Bioorg Med Chem Lett 18: 4232-6 (2008) Article DOI: 10.1016/j.bmcl.2008.05.064 BindingDB Entry DOI: 10.7270/Q26Q1VJM
					More data for this Ligand-Target Pair