BDBM290309 (−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-yl)pyrimido[1,2-b]indazol-2(1H)-one hydrochloride::US10098883, Example 52::US10668071, Example 52
SMILES: CCOc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNC(C)C1
InChI Key:
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen (aa 101-181) (Homo sapiens (Human)) | BDBM290309 ((−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-y...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel... | US Patent US10668071 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (aa 101-181) (Homo sapiens (Human)) | BDBM290309 ((−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-y...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall... | US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM | |||||||||||
More data for this Ligand-Target Pair |