BDBM29158 3-carboxamido coumarin, 8
SMILES: Cc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1
InChI Key: InChIKey=XUNAVIWFCXQWCJ-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM29158 (3-carboxamido coumarin, 8) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Universita degli Studi di Roma La Sapienza | Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide... | J Med Chem 52: 1935-42 (2009) Article DOI: 10.1021/jm801496u BindingDB Entry DOI: 10.7270/Q2SF2THN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM29158 (3-carboxamido coumarin, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O... | Eur J Med Chem 80: 278-84 (2014) Article DOI: 10.1016/j.ejmech.2014.04.060 BindingDB Entry DOI: 10.7270/Q2S46TJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM29158 (3-carboxamido coumarin, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Roma La Sapienza | Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide... | J Med Chem 52: 1935-42 (2009) Article DOI: 10.1021/jm801496u BindingDB Entry DOI: 10.7270/Q2SF2THN | |||||||||||
More data for this Ligand-Target Pair |