BDBM292044 2-Methyl-3-(7-methyl-1H-indazol-5-yl)-5-(trifluoromethyl)-2H-pyrazolo[4,3-::US10100045, Example 15

SMILES: Cc1cc(cc2cn[nH]c12)-c1n(C)nc2ccc(nc12)C(F)(F)F

InChI Key: InChIKey=HWDPNSZBUOFLEZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-2 subunit (Homo sapiens (Human))	BDBM292044 (2-Methyl-3-(7-methyl-1H-indazol-5-yl)-5-(trifluoro...) Show SMILES Cc1cc(cc2cn[nH]c12)-c1n(C)nc2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C16H12F3N5/c1-8-5-9(6-10-7-20-22-13(8)10)15-14-11(23-24(15)2)3-4-12(21-14)16(17,18)19/h3-7H,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...				US Patent US10100045 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K56
					More data for this Ligand-Target Pair